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For instance, mitochondrial augmentation therapy (MAT) for children with single large - scale mitochondrial DNA deletion syndromes (SLSMDs) showed no serious side effects, no immune rejection, normal blood/metabolism, and higher mtDNAbut this is preliminary (205)

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Inhibitory effects of IL-6 on IGF-1 activity in skeletal myoblasts could be mediated by the activation of SOCS-3