Non-soluble (soluble in oil), heavy metal, albeit volatile, pesticides, even some drugs
Later, the same group discovered that mice that lacked NFB in astrocytes had reduced Mn-induced glial activation and neuronal loss (Hammond et al., 2020)
doi: 10.1038/s41531-024-00724-z 36
Relationship between dietary sodium intake, body mass index and age-related cataract
Tanshinone IIA can inhibit focal death by modulating Txnip/NLRP3 inflammatory vesicles, regulation of TGFB1 inhibits high glucose-induced inflammation and cellular pyroptosis in renal tubular epithelial cells, may promote defense against DKD by inhibiting apoptosis caused by intracellular oxidative stress, can prevent podocyte damage in DKD by promoting autophagy and inhibiting inflammation, in part by inhibiting the PI3K/Akt/mTOR signaling pathway (Li et al., 2024), also ameliorates DKD-induced renal fibrosis by regulating miRNA-34a-5p in in vitro and in vivo studies
Mitochondrial ROS, ER stress, and nrf2 crosstalk in the regulation of mitochondrial apoptosis induced by arsenite