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The first molecule, developed by Novo Nordisk, is a fatty-acylated GIP/GLP-1 dual agonist, showed to improve glycated hemoglobin and to reduce bodyweight in patients with T2DM, compared to liraglutide in a Phase 2 clinical trial [18], (whereas no Phase 3 clinical trials are currently ongoing)
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IGF-1 cannot overcome the GH-induced resistant state (Kim & Park, 2003)
Access this chapter Subscribe and save Buy Now Tax calculation will be finalised at checkout Purchases are for personal use only Similar content being viewed by others References Kaelin WG Jr, Pallas DC, DeCaprio JA et al (1991) Identification of cellular proteins that can interact specifically with the T/E1A-binding region of the retinoblastoma gene product
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