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Decreased mRNA expression of SOD1 or SOD2 was also reported in HepG2 cells treated with fatty acids (Jain et al

Journal of Applied Microbiology

10 Also, when challenged with CD4+CD45+Rb(hi) lymphocytes, these mice experienced diarrhea and demonstrated increased susceptibility to colitis

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NAD+ repletion restored NAD+ metabolic profiles, improved fat metabolism, lowered mitochondrial oxidative stress, and improved mitochondrial integrity in human cells with mutant WRN via restoring normal mitophagy (25)