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Notably, this sgRNA enabled efficient on-target integration with no noticeable off-target editing in the context of in vivo knock-in, as demonstrated in a previous study 20

Klykov, O., Gangwar, S

Unlike compounds that target vascular smooth muscle, PT-141 is used in experimental models to explore peptide-mediated communication between the central nervous system and endocrine pathways

After reconstitution with bacteriostatic water, refrigerate at 28C and use within ~28 days

(b) the paracellular route used by ions, water and larger hydrophilic compounds from ~400600 Da up to 1020 kDa and that cannot cross transcellularly [regulated by the tight junction (TJ) proteins]