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In humans, they can cause esophageal cancer and impact the nervous system

ROS is a known inducer of cell proliferation (73)

Additionally, in STZ-induced diabetic rats, activity of membrane-bound DPP4 was increased, thereby reducing cardiac SDF-1 concentrations and causing impaired angiogenesis (174)

they might slow down future injections or ensure you havent taken other vasodilators (like hot drinks or exercise immediately prior) that could amplify that effect

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One possible alternative is Mounjaro (tirzepatide)