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This biological reversal typically begins within days and intensifies over weeks, creating a powerful drive to eat more food than before treatment started

Addiction Biology, 23(1), 7083

Insulin resistancewhen cells become less responsive to insulinaffects approximately 38% of US adults with prediabetes and represents a critical pathway to type 2 diabetes and cardiovascular disease

It helps to protect liver cells from damage caused by free radicals and toxins, and supports overall liver function

The patients must be encouraged to follow the specific recommendations to avoid/mitigate diarrhoea (Table 2, Figure 1, Figure 2 and Figure 3), which should already have been taught to them as part of their education prior to GLP-1 RA initiation

Management of these patients typically involves consultation with nephrology or endocrinology due to the complexity of mineral metabolism disorders