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These data are in agreement with the observation that DSF on its own decreases H 2 S production, although with a limited effect, but has an increased effect (as well as increased toxicity) when combined to copper (Supplementary Figures 2A, B)

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A study by Liou (65) revealed that CD133 can modulate cell cycle progression by affecting Wnt signaling and promoting the invasiveness of tumor cells (64-67)

Folates are also B group, water-soluble vitamins, which serve as coenzymes in a variety of reactions

Currently, western medical treatment of ACD mainly involves the use of topical corticosteroids and antihistamines, which are highly effective (Ta et al., 2021)