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This indicates that antioxidant property of Sp encompasses replenishment of intracellular glutathione, probably through inhibition of its breakdown

Glutathione operates in the aqueous intracellular environment where many oxidative reactions occur

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This is why tirzepatide appears to have broad therapeutic potential including weight loss, appetite suppression, cardioprotection, and more

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thus, the metabolic alterations identified may reflect biases inherent to previously studied metabolites