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Sirt-1 is required for the inhibition of apoptosis and inflammatory responses in human tenocytes

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These findings suggest that addressing zinc deficiency in older populations may alleviate systemic inflammation and oxidative stress, thereby reducing the risk of atherosclerosis and improving cardiovascular outcomes [477]

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Further supporting this notion, GarcaVega and colleagues recently reported that semaglutide improved the antithrombotic profile of patients by modulating the endocrine activity of epicardial adipose tissue, altering neutrophil phenotype, and reducing endothelial adhesion [115]