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GLP-1 Pipeline Update: August 2025 Quarterly view of the GLP-1 pipeline and anticipated indications Editorial team Maryam Tabatabai, PharmD Editor-In-Chief Associate Vice President, Clinical Information Carole Kerzic, RPh Executive Editor Drug Information Pharmacist Principal Nicole Kjesbo, PharmD, BCPS Executive Editor Clinical Program Development Director Senior, Pipeline DISCLAIMER The drug pipeline is fluid

J Neurol Neurosurg Psychiatry

While results vary, the strain choices-Akkermansia muciniphila, Clostridium butyricum, and Bifidobacterium infantis-are consistent with the stated purpose of supporting appetite and blood sugar regulation through the gut

The triple-agonist structure targeting three receptors instead of one makes synthesis significantly more complex

Biomarkers like neutrophil gelatinase-associated lipocalin (NGAL) have shown promise in predicting AKI in the immediate post-transplant period, offering a potential tool for early intervention

Examples: olive and flax oils, avocados, nuts and seeds, fatty fish