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Wet weight (mg) of liver per ml of total homogenate for each group of rats was calculated and using this value and concentration of GSH in liver cytosol fraction for each group, the GSH content of liver (moles g -1 wet weight) was determined as presented in Table 1

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10.1111/rda.13916 14

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Tirzepatide represents an important step in this direction, but further advances in triple agonism, oral formulations, and personalized medicine approaches will likely continue to reshape treatment paradigms