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Twice-weekly sessions during the first month tend to accelerate early progress

You typically start at 0.5 mg per week and increase every four weeks through 1 mg, 2 mg, 4 mg, and 8 mg to the target dose of 12 mg per week

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Injections are more effective for those with absorption issues or severe deficiency, but oral supplements work well for most people with mild deficiency and normal absorption