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These medications are expected to become more widely available this year, and demand for prescriptions is projected to climb substantially

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Recent research supports what clinicians are seeing

Active Gastrointestinal Fluid Losses For a subset of patients, especially during initiation or dose-escalation phases, gastrointestinal side effects can be pronounced: Nausea: Constant, low-grade nausea frequently creates a psychological aversion to swallowing anything, including plain water

Scrocchi LA, Brown TJ, MaClusky N et al (1996) Glucose intolerance but normal satiety in mice with a null mutation in the glucagon-like peptide 1 receptor gene