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Youre at risk of vitamin B12 deficiency
The primary theoretical concern is that sustained NAD+ elevation through chronic NNMT inhibition could activate pathways (PARP, SIRT1) that have context-dependent roles in cancer biology NAD+ supports DNA repair and cellular longevity, but also fuels rapidly dividing cells
Therefore, monitor these two, and you may want to increase your potassium intake in the first few months of injecting
What Tirzepatide Feels Like, Week to Week The most commonly described early effect is quieter food noise: less background pull toward snacks and less negotiation over each meal
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