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in Nature Medicine found that NNMT inhibition in white adipose tissue increased energy expenditure and reduced fat mass in animal models without altering food intake or physical activity (Kraus et al., Nature Medicine )

Criteria for necrosis included karyorrhexis (loss of nucleus) and/or degeneration of cytoplasm with either coagulative or liquefactive changes

Additional derived parameters were calculated

Animal metabolism differs significantly from human metabolism

Efficacy in Humans : Gastrointestinal Benefits : For individuals with gut issues, oral BPC-157 may provide general anti-inflammatory benefits

Inflamm Bowel Dis (2013) 19:1