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A Spanish University also did some research and found that Argireline increased the level of skin moisturization and decreased both the depth and width of wrinkles "significantly"

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doi: 10.1210/en.2013-1934

As a substance competing with intestinal Trp metabolism for precursors, MLT also participates in the dynamic modulation of M1/M2-type macrophage balance (94), which in turn reduces serum pro-inflammatory cytokine levels and restores intestinal barrier function