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On one hand, it mediates the cholinergic anti-inflammatory pathway, which involves inhibiting the production of inflammatory factors by peripheral macrophages through the release of acetylcholine, thereby controlling systemic inflammation (Li et al., 2024)

This can lead to symptoms like dizziness, fainting, and fatigue, which can affect daily activities and quality of life

The orbital fat, on the other hand, remains relatively stable

Many patients report that they expected significant pain but felt only mild pressure or a small pinch

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Further studies are needed to understand the effect of GLP-1RAs in other ethnic populations