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The direct antioxidant activity of this compound, demonstrated by its potent OFR scavenging capacity (48% maximal reduction), likely represents its primary mechanism of action [3]

Galant et al., 1999

Intriguingly, recent research highlights that ionizing radiation can trigger ferroptosis in certain cancer cells by amplifying lipid peroxidation [186, 187]

Because of the risk of birth defects, Accutane is regulated under a special safety program called iPLEDGE, which requires monthly check-ins, lab monitoring, and strict pregnancy prevention protocols for eligible patients

5-Amino-1MQ selectively inhibits NNMT (IC50 = 1.2 M), an enzyme that consumes nicotinamide by methylating it

Cardiovascular comorbidities of psoriasis and psoriatic arthritis: a report from the GRAPPA 2012 annual meeting