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Absorption Injected free B12 diffuses through the extracellular fluid into nearby capillaries, enters the bloodstream and binds to TCII (transcobalamin II)
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But they were designed for insulin, not peptides, and this creates a translation challenge that confuses many researchers
These are absolutely bloody marvellous
b) Transsulfuration: homocysteine is converted into cystathion by the enzyme cystathion B synthase (CBS) and the presence of cofactors vitamin B6 and haem
Another proposed mechanism involves the binding of homocysteine to the collagenous matrix of bone, which may modify collagen properties and reduce bone strength (reviewed in 113)
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