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The clinically relevant reductions in weight and SBP along with proven CV benefits in the SUSTAIN 6 trial support its preferred use in persons with established CV disease

Symptoms Both can cause: Nausea and vomiting Feeling full after eating only a small amount Bloating Upper abdominal discomfort Poor appetite Weight loss in some cases Blood sugar fluctuations in people with diabetes Gastroparesis = the medical diagnosis of delayed stomach emptying due to impaired stomach muscle function

Do not wait for your next review call your treating doctor, or in an emergency dial 112

The Numbers Are Eye-Opening : - Approximately 63% of people stop using GLP-1 medications within the first month - Nearly 70% stop within the first year The Most Common Reasons : - Persistent nausea - Constipation - Diarrhea - Vomiting - Fatigue - Loss of enjoyment of food - GI discomfort that impacts daily life For many people, the side effects outweigh the benefits long before long-term weight loss is achieved

In March 2024, Wegovy was also approved to reduce the risk of cardiovascular death, heart attack and stroke in adults with cardiovascular (heart, blood vessel) disease and either obesity or overweight

CertifiedTM: June 2025 - GLP-1s and Lean Mass: What the research shows