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People with chronic kidney disease, due to reduced kidney functions and reduced excretion 8

In the context of fip cat, maintaining adequate B12 levels is crucial due to its immune-enhancing properties and its involvement in red blood cell synthesis, nervous system function, and intestinal health

doi: 10.1007/s00109-016-1488-y

Higher muscle use and metabolic demand can increase vitamin D and B12 requirements, especially without adequate intake or sun exposure

These observations have led to the development of Mc4 receptor agonists