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Recently, large-scale randomized clinical trials have been conducted to assess the cardiovascular safety of these medications

Within days to weeks of stopping treatment, patients generally experience return of appetite to pre-treatment levels, faster gastric emptying, and loss of the medication's effects on satiety signaling

S.von ScholtenB

Without that foundation, even tirzepatide remarkable efficacy will be compromised by poor dietary choices, sedentary behavior, or chronic sleep deprivation

Reuters (2023)

In clinical trials, some of the stronger medications like Wegovy and Zepbound have been found to help people lose at least 10% of their starting weight