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This includes COL1A1 and COL1A2 (coding for Collagen Type I), COL3A1 (Collagen Type III), and ELN (Elastin)
and a recent intravenous safety pilot involved just two healthy adults
MH-OR, Mantel-Haenszel odds ratio
J.Prez-SalaD
A multicenter, open-label, exploratory phase Ib study assesses the safety, immunogenicity, and initial efficacy of the mRNA-based cancer immunotherapy BI1361849 (CV9202) in conjunction with local radiotherapy for patients with stage IV non-small-cell lung cancer (NSCLC) who exhibit stable disease or PR following first-line chemotherapy or EGFR-TKI therapy
On the basis of such standard assays, different isoforms are hereinafter referred to as enzymatically active or inactive glutaredoxins for the sake of simplicity (without excluding the possibility that inactive isoforms might actually catalyse other reactions with specialized substrates in vivo )
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