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The peak area ratio of analyte to its internal standard was converted to a concentration using a 1/ x weighted linear fit calibration curve (58)

GLP-1 agonists were initially developed to manage type 2 diabetes, and some studies have shown evidence that they might have positive effects on cardiovascular health

3739 While it is encouraging that the weight loss achieved with GLP-1/GIPGLP-1 receptor agonists approaches levels typically seen after bariatric procedures such as gastric bypass or sleeve gastrectomy, the rapid regain of a significant portion of the lost weight after treatment discontinuation, accompanied by a reduction in lean body mass, raises new clinical concerns

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