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A 2025 matched-cohort study found men who started testosterone therapy had significantly higher rates of tendon tears and repairs at one and two years compared to controls, a pattern the authors attributed to testosterone's effect on tendon biomechanics outpacing the tissue's regenerative capacity Sherman et al

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FDA scientists recommended against adding all seven to the compounding list, citing inadequate human trials and unresolved questions about contamination, immune reactions and dosing

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doi: 10.3389/fmicb.2025.1526250 Received 11 November 2024 Accepted 13 January 2025 Published 03 February 2025 Volume 16 - 2025 Edited by Sebastian Guenther, University of Greifswald, Germany Reviewed by Eugene A

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