Among patients also receiving metformin immediate-release, the median daily insulin (pre-mixed, intermediate or long acting) dose at baseline was 40 units in the sitagliptin-treated patients and 42 units in the placebo-treated patients
Extended Figure Legends Extended Data Fig
Another study also showed exendin-4 significantly reduced oxidative stress and apoptotic cells through restoring the cytokine-induced reduction of electron transport chain proteins of mitochondria 11
The SURPASS-3 MRI substudy demonstrated significant reductions in liver fat content at 52 weeks
We mentioned the 2022 Diabetes Guideline Cheat Sheet in the podcast you can get that for free at pyrls.com/rlp Liraglutide has a fairly low risk of hypoglycemia when used alone, but this risk increases when it is used with insulin or sulfonylureas
Study authors scoured the electronic health record of 18,386 people taking either Mounjaro or Ozempic between May 1, 2022 (the month Mounjaro received FDA approval) and September 30, 2023
