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Treatment goals: Jardiance provides modest weight loss with added heart and kidney benefits, while Ozempic and Wegovy typically lead to more substantial long-term weight loss

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doi: 10.3233/JPD-179005 21 GrosuA

The obesity medicine specialty has grown substantially as effective medications have become available

The tolerogenic mechanism is elegant: by presenting histone epitopes in a context that promotes regulatory rather than effector T cell responses, these peptides essentially re-educate the immune system to tolerate its own nuclear components