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While many of these studies are based on animal models, early human trials and anecdotal reports suggest promising results

Higher concentration doesn't automatically mean better results and can increase irritation risk

10.1155/2020/3626120 15 HuangB.LiangS.LiX.XieZ.YangR.SunB.et al (2024)

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In the presence of high concentrations of polyamines the ribosome frameshifting occurs resulting in the synthesis of functional antizyme 1 which comprises amino acids from both ORF1 and ORF2