Data availability The atomic coordinates and electron microscopy maps have been deposited in the Protein Data Bank (PDB) and Electron Microscopy Data Bank (EMDB) under accession codes: 9BP3/EMD-44760 [ (Cagri-AMY 1 R-DNG s complex), 9BLW/EMD-44678 [ (CagriBB-AMY 1 R-DNG s complex), 9BQ3/EMD-44796 [ (Cagri-AMY 2 R-DNG s complex), 9BTW]/EMD-44898 [ (Cagri-AMY 3 R-DNG s complex), 9BUB/EMD-44904 [ (Cagri-CTR-DNG s complex 1, bypass conformation), 9BUD/EMD-44906 [ (Cagri-CTR-DNG s complex 1, CT-like conformation), 9BUC/EMD-44905 [ (Cagri-CTR-DNG s complex 2, bypass conformation), 9BUE/EMD-44907 [ (Cagri-CTR-DNG s complex 2, CT-like conformation), 9BLC/EMD-44653 [ (CagriBB-CTR-DNG s complex 1, CT-like conformation), 9BLB/EMD-44652 [ (CagriBB-CTR-DNG s complex 1, bypass conformation)
For Wegovy, this involves starting at 0.25 mg weekly for 4 weeks, then increasing through 0.5 mg, 1 mg, 1.7 mg, and finally to the 2.4 mg maintenance dose, with each step lasting 4 weeks
Westerterp-Plantenga MS, Lemmens SG, Westerterp KR
doi:10.1097/PRS.0000000000009876
Data availability The datasets generated and/or analyzed during the current study are not publicly available because they contain PII (birthdates) but are available in a de-identified fashion from the corresponding author on reasonable request
While we focus mainly on analyzing inspection-based warning letters, we also offer general context on all warning letters for these product categories