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Data was graphed after normalizing each insulin time course by dividing by the secretion rate at each time point by the rate obtained in the presence of 20 mM glucose prior to the addition of test compounds

Eghtesadi, A

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Moreover, our findings suggest that this paracrine feedback loop can be harnessed through the administration of GLP-1R agonists

High-glucose-induced metabolic and redox alterations are distinctly modulated by various antidiabetic agents and interventions against FABP5/7, MITF and ANGPTL4 in melanoma A375 cells