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These adverse effects were likely to be due to pre-existing factors i.e

Besides these compounds, the plant contains flavones, anthraquinones, hentri-acontane, pentatriacontane, and -chlorophylls, phytin, resins, d-quercitol, tartaric acid, formic acid, butyric acid, lupeol, -amyrin related glycosides and stigmasterol

M., & Wilcox, C

Research in GeroScience shows that mitochondrial glutathione plays a key role in protecting against age-associated oxidative damage