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Ann Clin Psychiatry (2009) 21:21336

AGEs disrupt the dynamic balance of the skin (84), alter the normal substance composition and structure of different skin layers, impair the skin barrier function, and trigger skin issues

Thus, a mutation in the TP53 gene could confer protection against ferroptosis in a specific manner

5.3.1 Vitamin Microbiota-related vitamins contribute to barrier integrity by regulating tight junctions, epithelial permeability, and epigenetic programs (133, 134)