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Different conditions, like esophageal varices and gastroesophageal reflux, can cause esophageal bleeding, ultimately revealed as black and tarry stool symptoms

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Diabetic patients exhibit elevated chronic oxidative stress and inflammation (Li et al., 2025), exacerbating MIRI injury with larger infarcts and poorer outcomes (Sztolsztener et al., 2022), potentially due to hyperactive ROS sources and impaired defenses

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doi: 10.1093/oxfordjournals.humrep.a019263 162 FernandezJLMurielLRiveroMTGoyanesVVazquezRAlvarezJG