incretin mimetics glp 1 agonists A Brief Review of Intended for the Management of Diabetes and Associated Comorbidities[v1] Schematic Mechanism of Incretin mimetics

GLP1 agonists work by promoting insulin secretion, which helps maintain blood sugar levels among type 2 diabetics

10.1016/j.lfs.2014.09.028 40

Studies have demonstrated that GLP-1RAs promote AMPK2 activation by inhibiting miR-27a expression in breast cancer cells

Endocr Rev 2014;35:9921019.ArticlePubMedPMC 23

Cholinergic neurons of the enteric nervous system, which interact closely with gastrointestinal epithelial cells, as well as ACh signaling in non-neuronal cells such as enteric glia and pancreatic cells, depend on the essential role of thiamine in ACh production and the facilitation of ACh signaling

TABLE 2 Clinical outcomes of the selected cohort under investigation