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Instead, its effects on wakefulness appear to be a downstream consequence of its interaction with major neurotransmitter systems

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Adding to doctors worries are concerns about purity and dosing, because users typically buy from websites selling unregulated Chinese product some of which comes from plants that previously produced the deadly opioid fentanyl

This makes compliance not only a clinical concern, but also a financial one

I know that one of the results of our online petition at the Welsh Government was that the Chief Medical Officer advised that if patients needed more frequent injections then they should supplement with oral tablets

J Neurosci Off J Soc Neurosci (2013) 33(26):1082839