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In a micellar environment GLP-1 assumes a structure with an Nterminal random coil segment and two helical segments separated by a linker region (112)

The only area where it gained some interest was as a means to help terminate hypoglycaemia in schizophrenic patients given insulin shock therapy (figure 13)

Another meta-analysis showed that HbA1c was reduced 2.1% and body weight 8.6kg with 15mg dose

Insulinotropic effects associated with GLP-1-like peptides have been reported in a range of venomous species including arthropods, reptiles 32,33,34,35,36 , and recently in cone snail venom, which induces severe hypoglycemic shock in its fish prey 16

518 This was observed through improved glycemic control, reduced occurrence of liver cancer, and better liver histology compared to the control group