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Is there a step therapy requirement, do I have to try another medication first

But here's the twist: when the glucagon receptor is activated in conjunction with GLP-1, particularly at higher doses, it can lead to increased energy expenditure and direct effects on liver fat reduction

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[4] Short-course oral NSAID when acetaminophen fails: Ibuprofen 200-400 mg with food and water, 1-3 days maximum, only if well-hydrated and kidney function is normal

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Symptoms include localised injection site redness and swelling, or systemic signs such as widespread hives, facial swelling, breathing difficulty, or cardiovascular collapse