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Do not use this therapy during pregnancy and breastfeeding

alternatives include SGLT2 inhibitors, DPP-4 inhibitors, insulin, or specialist allergy assessment for switching agents

Not optional, not recommended, but required for maintaining the 28-day beyond-use date and preventing bacterial colonization

They can help determine if your specific situation warrants additional antioxidant support

Important safety considerations include contraindications in patients with personal or family history of medullary thyroid carcinoma or multiple endocrine neoplasia syndrome type 2, caution in those with a history of pancreatitis, increased risk of gallbladder disease, potential for acute kidney injury with dehydration, and possible worsening of diabetic retinopathy with rapid glycemic improvement

Common genes: HNF1A, HNF4A, GCK