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Characterization of a patient-derived variant of GPX4 for precision therapy
doi: 10.1111/dom.14725, 96
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361 Interestingly, in a 2.5% dextran sodium sulfate-induced mouse model of colitis, mice fed a high-fat diet presented significantly reduced expression of markers of lipid peroxidation and ferroptosis in the gut in a manner independent of obesity, protecting the gut from inflammatory damage by inhibiting ferroptosis
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