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Additionally, hormonal variations, particularly fluctuations in estrogen levels, have been shown to affect ligament laxity and strength, further contributing to the higher incidence of ACL injuries in females

Three studies presented or published in the past year changed how I talk about this in clinic

Still, cravings may return during high-stress periods, social events, or times of emotional upheaval

Rarely, long-term use without medical guidance can lead to ochronosis, a bluish discoloration of the skin

Jorgensen, R., Martini, L., Schwartz, T

Then follow the dosage escalation schedule in Table 1, titrating every 4 weeks to achieve the maintenance dosage