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Data availability The datasets generated and/or analyzed during this study are not publicly available because they are stored on the corresponding authors personal account on the Stampede3 supercomputer

NAD+ levels in our bodies naturally drop as we age, falling by half when we reach our 40s

A metallic or faintly ammonia-like smell suggests breakdown

Kempermann G et al (2004) Milestones of neuronal development in the adult hippocampus

Compounded semaglutide is a preparation of the active ingredient semaglutide made by a licensed compounding pharmacy based on a prescription from a licensed provider