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Side-effect context matters for people with diabetes, dehydration risk, kidney disease, gallbladder disease, severe reflux, gastroparesis (delayed stomach emptying), or a history of pancreatitis

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This goes beyond managing diabetes and obesity to include neurodegenerative diseases of the central nervous system

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The guidance outlines five key recommendations relating to GLP-1RAs and GLP-1/GIPRAs and sedation or anaesthesia: All patients should be asked about the use of GLP-1RAs and GLP-1/GIPRAs before anaesthesia or sedation for surgical and endoscopic procedures and be involved in discussion and planning regarding the risk of aspiration

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