GLP-1s, like semaglutide and tirzepatide, are medications that work by mirroring naturally occurring hormones in the body
Activation of central trigeminovascular neurons by cortical spreading depression
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A larger follow-up RCT (n=72 older adults) confirmed these findings, additionally demonstrating improvements in gait speed (+0.14 m/s), grip strength, 6-minute walk distance, waist circumference reduction, and systolic blood pressure reduction (Kumar et al., J Gerontol A Biol Sci Med Sci, 2023) [21]
Retatrutide Titration Chart This chart represents a common structure, but your provider may modify it depending on your tolerance and goals
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