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In agreement with experimental studies, GLP-1 analogues, particularly liraglutide, sustain the maintenance of -cell function in obese individuals with early T2D, and these effects are presumably independent of weight loss (42, 43)
Scientific Considerations on Transdermal Peptide Delivery Skin acts as a protective barrier
Nonetheless, a recent review including rodent studies supports the notion that GLP-1 has differential effects before compared to after a meal (Decarie-Spain & Kanoski, 2021)
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Follow-up appointments are on a case-by-case basis