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T., Beat, A., Singh, A

Among participants who took the tablet exactly as prescribed, average weight loss reached up to 16.6% (compared with 2.7% on placebo), and around 30% of people on the tablet lost 20% or more of their body weight

spin-out built around Hengrui-licensed incretin assets - IPO'd in 2025 with HRS-4729 as part of a portfolio anchored on HRS9531 (a dual GLP-1/GIP agonist that read out ~17.7% weight loss in Phase 3 in China in February 2026)

Cartwright, Monitoring Report: GLP-1 RA Prescribing Trends December 2025 Data

Increased urination may correlate with early weight loss and metabolic adaptation, but it is not a reliable indicator of medication effectiveness

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