MAT1 KO hepatocytes can also be detected with reduced methylation/CYP2E1 ratio, reduced mitochondrial membrane potential, increased ROS content, and are sensitive to ethanol and TNF--induced mitochondrial dysfunction
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San Martn A, Du P, Dikalova A, Lassgue B, Aleman M, Gngora MC, et al
Acknowledgements The study is supported by a Singapore EDB-IPP grant (grant number: RL2012035)