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Orforglipron (Eli Lilly) is the first non-peptide oral GLP-1 receptor agonist a small molecule rather than an injected peptide, with no SNAC absorption-enhancer required and an FDA decision is anticipated in 2026

Its also suggested to have a sharps disposal container nearby for disposing of the injection immediately after administration

Understanding different water choices helps you decide which option supports your method

For a deeper look at how GLP-1 medications may influence nutrient intake, explore our registered dietitians guide to GLP-1 supplementation

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