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Oct 22 2022;15(1):329

Subsequently, the Cys-Gly dipeptide is degraded by membrane-bound Anpep to yield cysteine and glycine for another glutathione cycle

Mechanistically, GSH depletion does not cause global protein oxidation but instead selectively oxidizes and destabilizes fatty acid synthase while decreasing lipogenic gene expression at the transcriptional level, collectively suppressing lipogenesis

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Pyroptosis, a programmed cell death mechanism, plays a critical role in the pathogenesis of both RP and LPS-induced pneumonitis

Genetic disease like sickle cell anemia or thalassemia