This is a preview of subscription content, access via your institution Access options Subscribe to this journal Receive 12 print issues and online access $259.00 per year only $21.58 per issue Buy this article Purchase on SpringerLink Instant access to the full article PDF
C., Cheiran, G., Rocha, M
Genetic Findings of GSH GS deficiency is a rare disorder of glutathione (GSH) metabolism manifested in children by severe metabolic acidosis with high urinary level of 5-oxoproline (pyroglutamic acid), hemolytic anemia, and neurological events
This can lead to an increase in blood flow to the brain, which can cause a temporary increase in intracranial pressure and result in a headache
Vitamin C elevates red blood cell glutathione in healthy adults
Such dysfunction in permeability is evidenced by heightened urea uptake and positive responses to potassium sensitivity tests in patients with IC (Sant, 2002)